Thursday 12 October 2017

Falling in Love - The Story of Progesterone

Progesterone is produced as a tablet. This is a steroid tablet and is used as a drug to go "high" - anabolics.




But what is the real implication of this drug in our lives? We need to know more.


Courtesy: Britannica




Biological Role of Progesterone:


I do not intend to focus more on this perspective of progesterone which is well-established and is very well known to many of us. In a gist the role of progesterone has the following physiological effect every month in a successful ovulatory cycle:


1. The secretion of egg stimulates the follicle cells by the lutenising hormone to secrete less progesterone and estrogen. This continues till successful ovulation and formation of corpus luteum.

2. The corpus luteum starts to secrete progesterone. This is to aid in the preparation of the utreus to receive this egg in a bed of tissue that will provide, anchor for development of baby with enough blood supply, oxygen and nutrients.


3. The progesterone secretion continues until the peak is reached and the egg is received. If the egg is a fertilised egg the secretion of progesterone will continue. If not the unfertilised egg will stimulate the inhibition of progesterone and estrogen secretion leading to bleeding with discharge of disintegrated tissues in the uterine lining.


These are the 3 primary roles of progesterone in biological cycle.


The following chart displays level of hormones as monthly cycles:

Courtesy: Barclays



This is  CLUE as why and what people are doing and will have an implication on the monthly synchronised cycles to the biology of individual's physiology by doping with modus. PLEASE STOP!!!


Copulatory Behavioral Role of Twin Hormones:


Esterogen: Estrogen are known to do the following: female willingness to approach a male; increases the attractiveness of the female and "primes" for progesterone.


Progesterone: Progesterone has a dual role: in small amounts this will incease and supplement estrogen activity to sexual receptivity to men and libido effects during sexual intercourse; while continued use of progesterone will increase the tendency to reject sexual activity and indulge in nurturing the developing baby if pregnant. If not pregnant, this is when the contraindications of prolonged abuse of progesterone tablets will be effective.


Common contraindications of progesterone: Fatigue, dizziness and an increase appetite. There may be more severe and serious symptoms like breakthrough bleeding, menstrual cramps, bloating caused by water weight gain, moodiness, nausea, irritability and tiredness. They mimick PMS but are not PMS. Very rare symptoms will include fainting, depression, severe headaches, vision problems, breast tenderness and trouble sleeping. Stroke, blood clots and heart attack are very rare effects.


Progesterones have the ability to inhibit bleeding while estrogens stimulate bleeding and increases bleeding levels. This is why progesterones are used to treat people with heavy bleeding or abnormal uterine bleeding (AUB).


Needless to say, without an active sex life the use of these hormone tablets, especially the doses of "birth control pills" is not recommended for the contrainidcations will be amplified. This is because the sexual activity by itself will arouse umpteen physiological elicitations in the body that may in turn will have an implication in reducing the side effects of these tablets.


Needless to say, please do not use these tablets without an appropriate health practitioner's consultation and use it only for yourself. This is why these are Schedule H drugs or prescription drugs that requires to be sold only with the prescription and administered by the physician only after consulting the patient in a proper manner.

N.B: Personal Email from Minister of WCD, India for taking action as despite reporting twice of drugsters red-handed for lack of knowledge and perspectives despite "lecture time" - I still, however, await to receive my FIR copy